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Once reconstituted, the solution should be kept refrigerated and is typically stable for up to 2 months under proper storage conditions

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However, using oral arginase inhibitors long-term to promote NO production may be challenged by the lack of isoform specificity, making it difficult to balance the roles of arginase isoforms in the urea cycle and NO production and potential disruption of nitrogen metabolism (Pudlo et al., 2017)

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